Should extrapulmonary small cell cancer be managed like small cell lung cancer?
نویسندگان
چکیده
منابع مشابه
KRAS Mutation in Small Cell Lung Carcinoma and Extrapulmonary Small Cell Cancer.
BACKGROUND Lung cancer is one of the most lethal cancers. It is mainly classified into 2 groups: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Extrapulmonary small cell carcinomas (EPSCC) are very rare. The Ras oncogene controls most of the cellular functions in the cell. Overall, 21.6% of human cancers contain a Kirsten Ras (KRAS) mutation. SCLC and EPSCC have several s...
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The management of small-cell lung cancer (SCLC) evolved rapidly through the 1980s, but has stalled since then. The relative roles of surgery and radiotherapy in this former systemic disease have been worked out well. The chemotherapy of SCLC has progressed less rapidly. This article discusses the latest developments in each modality of treatment of SCLC and summarizes current treatment strategies.
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wnloade development of metastases is the main reason for cancer-related death in non–small cell lung cancer LC). The initiation of metastasis involves an increase in cell motility mediated by the loss of cell-cell on caused by E-cadherin repression, in a process commonly known as epithelial-to-mesenchymal transirole for microRNA-200 family members in regulating epithelial-to-mesenchymal transit...
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Background: Small cell lung cancer (SCLC) is a highly aggressive tumor. Objective: To evaluate the survival and time to progression of patients with SCLC admitted to a chest disease center in Istanbul, Turkey. Methods: Based on the reports of a pulmonary oncology clinic, data regarding performance status (PS), clinical stage of disease, treatment, time to progression and survival of 67 patients...
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ژورنال
عنوان ژورنال: Cancer
سال: 2010
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.24858